The Not For Collies Drug List
Be aware of anything with “ictin” on the end. NOTE: the MDR1 test is simple and not too expensive but is vital to your herding dog’s health and life.
- Abamectin Antiparasitic Agent
- Acepromazine Tranqualizers
- Butorphanol Tartrate (Torbutrol, Torbugesic) Pain Control
- Cyclosporin Immunosuppressive agent
- Cyclosporin A Immunosuppressive agent
- Deramaxx
- dexamethasone, Steroids
- Digoxin Heart drug
- Domperidon Gastrointestinal Agents
- domperidone
- doramectin
- Doxorubicin Chemo drug
- Erythromycin Antibiotic
- etoposide
- Grepafloxacin Antibiotics
- Heartgaurd
- Hydrocortisone Steriods
- Immodium Loperamide
- Ivermectin Antiparasitic Agent
- Kaopectate (some formulas)
- Loperamide (e.g. Immodium AD) Gastrointestinal Agents
- Macrocyclic Lactones Anti-helminthic pharameuticals that are P-glycoprotein substrates include the family of compounds
- Milbemycin Oxime Antiparasitic Agent
- mitoxantrone
- morphine
- Moxidectin Antiparasitic Agent
- Ondansetron
- Oxorubicin Anticancer agents
- paclitaxel
- PeptoBismol (some formulas)
- Pro Heart6
- Quinidine
- Revolution
- rifampicin
- Rimadyl
- Selamectin Antiparasitic Agent
- Substrates for P-glycoprotien
- Tacrolimus Immunosuppressants
- Vinblastine Chemo drug
- Vinca Alkaloids Anticancer agents
- Vincristine Chemo drug
- *Drugs that are P-glycoprotein substrates can build up dangerous levels in the brains of genetically sensitive Collies
We learned that the “not for collie drug list” applies to a large percentage of herding breeds and a test can be given to test for the gene that some of these dogs are missing which keeps the drugs out of the brain.
The reason I tell you this, is that not all veterinarians are up to date on this, and we need to educate ourselves and them.
Please pass it to all collie and herding group people.
I encourage you to do the research and have the list put in their pet’s medical chart. Give it to your veterinarians.
This list may not be inclusive as new drugs are coming out all the time.
Does anyone know of any sort of side effects after the use of Silymaryn, an extract of the herb called Carduus Mariannus; in Rough Collies? I’ll appreciate any comments about it. Thanks!
There is a great website for people who have the breeds that the MDR1 gene mutation:
http://www.busteralert.org/
The volunteers keep this site very up to date.
Stephanie, thank you for that. 🙂
David, I just post what I find that might be helpful. Have to say I don’t know the answer to your question.
This is very up-to-date info. I think I’ll share it on Delicious.
References please!!!
I would like to know where this list came from? References? I have used several drugs on this list on all sorts of Collies over the last 50 years. I know Rimadyl is controversial and not just with Collies, but I have never seen it on any “not for Collies” lists. I can’t tell you how many Collies I have given Rimadyl to – it not only helped their pain issues but extended their lives.
My collie got liver failure from Rimadyl. She ended up dying. She was such a good girl 😥 I will never use it again. She was given it after surgery on her ACL.
I agree with Gayle Kaye. Milbemycin Oxime is interceptor. That one specifically has no place on this list. I would love to see some references. Whenever I have any questions about medications, I look to the Washington State University. The keep the list as up to date as possible.
The official list from Washington State University, with explanations of what we know of the actions and effects of each drug on the list: http://vcpl.vetmed.wsu.edu/problem-drugs